Morning, Marco. Monday, so the journals wake back up tomorrow — today's news is
mostly weekend accumulation. Three things moved: Puerto Rico is now several days
into scheduled water shutoffs and the mood has turned, the Pentagon is quietly
looking for a way out of the Iran fight, and the VA is about to run the biggest
test yet of semaglutide for alcohol use disorder. Nothing here needs a decision
from you. Coffee, seven minutes, then sleep.
ATop Stories
Update: Puerto Rico's rationing is no longer a plan on a website — it's people waking up with dry taps
The 48-hours-on / 48-hours-off schedule that started Friday is now in its
second full cycle, covering more than 180,000 AAA customers across San
Juan plus Carolina, Juncos, Gurabo, Trujillo Alto, Canóvanas and Loíza. The
driver is stark:
July was the driest month San Juan has recorded in more than 120 years
and its fourth hottest; roughly a quarter of the island is in severe drought
and another 36% in moderate. AAA is trucking water with priority to
hospitals and long-term care facilities, and telling residents to boil
for three full minutes once service returns, because pressure loss in old
distribution lines invites contamination. Rationing runs at least through the
end of August, and officials have floated stretching the cycle to 72 hours if
Carraízo keeps dropping. The
NPR piece from Sunday
is the one to read — the anger is now the story, not the drought.
Why it matters — Two reasons. Family first: if you're
calling the island this week, the schedule matters more than the weather.
Clinically, this is the setup for a predictable downstream pattern — boil
advisories after pressure loss produce GI illness clusters, and elderly
people ration their own intake when they're rationing storage, which shows
up in an ED three days later as an AKI with a bland sediment.
Talking point — Worth knowing that a U.S. jurisdiction
is prioritizing hospital water delivery by truck in 2026. If your group ever
revisits its own utility-failure contingency, this is the live case study.
Update: The chairman of the Joint Chiefs is privately pushing for an off-ramp on Iran — while the Houthis hit a Saudi refinery
Sources told
CNN on Sunday
that the chairman of the Joint Chiefs has made clear internally that the U.S.
needs a way out, because the remaining escalation options could backfire.
Meanwhile Houthi forces claimed a strike on Saudi Aramco's Jazan refinery
on the Red Sea coast, and the Pentagon sent a memo to defense contractors —
the war's industrial tail is lengthening. On the diplomatic track, Vice
President Vance told Fox News the U.S. goal is to "maximize" oil and gas
moving through Hormuz, but the IRGC said Friday that
reopening the strait is not governed by the Oman deal at all
— Tehran's list now includes ending the naval blockade of Iranian ports,
withdrawing forces, and permanently ending the war.
Why it matters — The route through the strait was agreed
more than a week ago and the strait is still shut. That gap is the whole
story: the technical negotiation and the political one have come apart, which
is why "close to a deal" has now been true for eight days running.
Watch for — A joint statement out of Muscat. Until
there's a signed document, treat the reopening headlines as forecasts.
The VA is about to run the largest trial yet of semaglutide for alcohol use disorder
Recruitment opens this month for CRAVE (Cessation or Reduction of
Alcohol Consumption in Veterans), a
phase 3, double-blind, placebo-controlled trial
across 18 VA sites, enrolling more than 600 veterans aged 18–80
with moderate or severe AUD, on weekly injectable semaglutide for 24 weeks.
It follows two smaller signals: a
CU Anschutz phase 2 of oral semaglutide
that missed its primary endpoint (lab-induced craving at six weeks) but
significantly cut heavy drinking days, naturalistic craving and
alcohol-related consequences; and a
Lancet RCT in patients with AUD and comorbid obesity.
Medscape's
write-up
is the efficient version.
Why it matters to you — Alcohol-related admissions are a
standing fraction of your census, and GLP-1s are already on a lot of your
med lists. Within a year or two the answer to "why is this patient on
semaglutide?" may be AUD rather than diabetes or weight — which changes what
you assume about their diet history, their gastric emptying before a
procedure, and how you read a withdrawal trajectory in someone who has been
quietly drinking less for months.
Suggested action — Nothing to change today. But it's a
clean five-minute agenda item for the next group meeting: does our admission
med-rec capture the indication for a GLP-1, or just the drug and dose?
Right now, for most shops, it's just the drug.
That's the lot. The only thing with a clock on it this week is the CY2027 OPPS
comment window, and that's three Mondays out. Sleep well, Marco.