2026 Surviving Sepsis Campaign guidelines are out — and older adults get a lower MAP target
The SCCM/ESICM 2026 update landed: 129 statements, 46 of them brand new, building on the 2021 edition. The headline for your patient population — in septic shock adults aged 65 and older, an initial MAP target of 60–65 mm Hg is now suggested over higher targets, backed by a meta-analysis showing lower mortality (RR 0.89, high certainty). Other new ground: antibiotic optimization, fluid removal after resuscitation, and — notably — post-discharge continuity including physical and psychological rehab.
Why it matters: most of your inpatients are exactly the 65+ cohort this recommendation carves out. If your order sets and nursing titration protocols default everyone to ≥65 mm Hg, that's now out of step with the evidence for your typical admit.
Talking point / action: flag the ≥65-year MAP target for your next sepsis order-set review, and mention the post-discharge rehab language to case management — it dovetails with transitions-of-care work. SCCM guideline · summary